A Video on TB-LAMP
Detect TB. Accurately. Easily.
The World Health Organization endorsed TB-LAMP as a failsafe solution
for peripheral diagnostic centres.
- Result for 1-14 Samples per batch in
< 2 hrs - Performance – 50 -60 samples in 8 hour shift
- Visual Detection & Interpretation
- No processing – Raw sputum is directly used as sample
- Sample required – Only 60 µL
- High sensitivity:
92-100% - High specificity:
96.6 – 100% - Capable of managing extra-pulmonary TB samples: CSF, Pus Cells, Lymph Nodes, Urine & Endometrial Fluids
- Lower training requirements
- Minimum infrastructural requirements: Bio-safety requirements similar to microscopy
- Room temperature shipment and storage: (1 – 30 oC)
- Alternate power sources: solar & battery
- Lower capital investment
- High economic
utilization
The TB-LAMP solution is best suited to make a credible impact onto the TB burden in India
No more missing out on 50% of TB cases4-5
TB-LAMP
When compared to Sputum Smear Microscopy
TB-LAMP: A front-line diagnostic test for TB suspect
Higher
Suspect Detection
TB-Lamp detects > 15%
more positive TB cases3
Additional
Sensitivity
40% additional sensitivity
in sputum negative cases
Turn Around
Time
One of the fastest TAT for molecular
diagnostic solutions
1-14 samples in a single run of < 2 hrs
Smear Microscopy Misses Every Alternate Case
TB-LAMPWhen compared to CB – NAAT
Sample Processing
Negligible Sample
Pre-processing
Raw sputum Is directly used as sample
Fastest TAT
1 – 14 Samples in < 2 hours
Bio- safety
1 – 14 Samples in < 2 hours
Easy shipment
Easy shipment
At Room Temperatures
(1 – 30 oC)
Sample Volumes
Low Sample Volume
60 µL
Please be informed that the cases diagnosed using TB LAMP
can be notified on the “NIKSHAY” portal and the test can be
indicated under the “others” column in the drop down.
TB-Lamp for
Lab Professionals
Clinician’s depend on lab professionals for making an informed clinical decision.
Being one of the high burden countries with TB, an accurate test like TB-LAMP can ensure that India’s TB burden is effective addressed.
TB-LAMP Offers Tangible Benefits Over Sputum Smear Microscopy
TB-Lamp for
Clinicians
TB-LAMP detects nearly all smear-positive and half of smear-negative TB cases and
has a high specificity when performed in reference laboratories. Performance was
similar to the Xpert MTB/RIF assay.4
TB-LAMP Offers Some Tangible Benefits Over CB-NAAT
TB-LAMP For
Public Health Professionals
TB-LAMP can be easily adapted at PHC/CHC level.
Lack of access to diagnostics is a major hinderance in driving an effective
TB program in India. TB-LAMP can play an effective role in addressing this challenge.
As compared to the other diagnostic tools, TB-LAMP offers significant benefit.
WHO recommends TB-LAMP can be used as a replacement of sputum smear microscopy.4
With its high sensitivity & specificity, TB-LAMP detects:
- >15% more positive TB cases3
- 40% additional sensitivity in sputum negative cases
Owning to its simplicity,
TB-LAMP is highly scalable
both geographically
as well as its throughput:
- 1-14 samples in a single run of <2 hrs
- Lower training requirements: 2-3 days for technology adoption
- Minimum infrastructural requirements: Bio-safety requirements similar to microscopy
- Room temperature shipment and storage: (1-30O C)
- Alternate power sources: solar & battery
TB-LAMP offers all the benefits
of a validated molecular diagnostic
test at a significantly
lower cost:
- Lower Cost of Ownership
- Lower Cost per Test
References:
1. WHO TB Report 2018
2. Indian J Chest Dis Allied Sci 2006; 48: 245-247
3. Perkins et al ; Int J Infect Dis. 2018 Mar; 68: 44–49
4. WHO -EDL 2018, 5- Kaku T.et al: Jap J Infect dis: Published online : March18
5. Kaku T.et al: Jap J Infect dis: Published online : March18
